Inhibitors | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | competitive inhibition; competitive product inhibition, overview | Oryctolagus cuniculus | |
pyridoxal 5'-phosphate | competitive inhibition | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.004 | - |
pyridoxine 5'-phosphate | enzyme activity in liver homogenate | Rattus norvegicus | |
0.008 | - |
pyridoxamine 5'-phosphate | enzyme activity in liver homogenate | Rattus norvegicus | |
0.011 | - |
pyridoxamine 5'-phosphate | enzyme activity in liver homogenate | Oryctolagus cuniculus | |
0.015 | - |
pyridoxamine 5'-phosphate | enzyme activity in cytosol | Oryctolagus cuniculus | |
0.016 | - |
pyridoxine 5'-phosphate | pure enzyme in 200 mM potassium phosphate pH 7.0 | Oryctolagus cuniculus | |
0.016 | - |
pyridoxine 5'-phosphate | pH 7.0, 37°C | Oryctolagus cuniculus | |
0.017 | - |
pyridoxine 5'-phosphate | enzyme activity in cytosol | Oryctolagus cuniculus | |
0.017 | - |
pyridoxine 5'-phosphate | enzyme activity in liver homogenate | Oryctolagus cuniculus | |
0.018 | - |
pyridoxamine 5'-phosphate | pH 8.0, 37°C | Oryctolagus cuniculus | |
0.022 | - |
pyridoxine 5'-phosphate | enzyme activity in liver homogenate in the presence of 0.005 mM pyridoxal 5'-phosphate | Rattus norvegicus | |
0.024 | - |
pyridoxamine 5'-phosphate | pure enzyme in 200 mM potassium phosphate pH 7.0 | Oryctolagus cuniculus | |
0.024 | - |
pyridoxamine 5'-phosphate | pH 7.0, 37°C | Oryctolagus cuniculus | |
0.025 | - |
pyridoxine 5'-phosphate | pH 8.0, 37°C | Oryctolagus cuniculus | |
0.039 | - |
pyridoxamine 5'-phosphate | enzyme activity in liver homogenate in the presence of 0.005 mM pyridoxal 5'-phosphate | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
pyridoxamine 5'-phosphate + H2O + O2 | Oryctolagus cuniculus | - |
pyridoxal 5'-phosphate + NH3 + H2O2 | - |
? | |
pyridoxine 5'-phosphate + O2 | Oryctolagus cuniculus | - |
pyridoxal 5'-phosphate + H2O2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Oryctolagus cuniculus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
native enzyme from liver | Oryctolagus cuniculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
liver | - |
Oryctolagus cuniculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
pyridoxamine 5'-phosphate + H2O + O2 | - |
Rattus norvegicus | pyridoxal 5'-phosphate + NH3 + H2O2 | - |
? | |
pyridoxamine 5'-phosphate + H2O + O2 | - |
Oryctolagus cuniculus | pyridoxal 5'-phosphate + NH3 + H2O2 | - |
? | |
pyridoxine 5'-phosphate + FMN | - |
Rattus norvegicus | pyridoxal 5'-phosphate + FMNH2 | - |
? | |
pyridoxine 5'-phosphate + O2 | - |
Oryctolagus cuniculus | pyridoxal 5'-phosphate + H2O2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
pyridoxamine (pyridoxine) 5'-phosphate oxidase | - |
Oryctolagus cuniculus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Oryctolagus cuniculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | 8 | assay at | Oryctolagus cuniculus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.003 | - |
pyridoxal 5'-phosphate | pure enzyme in 200 mM potassium phosphate pH 7.0 or enzyme activity in liver homogenate, substrate pyridoxamine 5' phosphate or pyridoxine 5'-phosphate | Oryctolagus cuniculus | |
0.003 | - |
pyridoxal 5'-phosphate | pH 8.0, 37°C | Oryctolagus cuniculus |